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ISNTD

ISNTD

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3

(diagnostics, drug discovery & development)

(diagnostics, drug discovery & development)

 

 

Dr.Philippe Büscher

Philippe Büscher is the head of the Unit of Parasite Diagnostics at ITMA and is specialised in the development, evaluation and production of diagnostic tests for Human and Animal African Trypanosomiasis. Recently the Unit has extended his activities towards diagnosis of leishmaniasis and of Chagas' disease, in close collaboration with a private company Coris BioConcepts.

 

The expertise of the Unit in diagnosis and stage determination is regularly appealed for by other groups that conduct clinical trials on novel drugs and drug combinations in HAT.  

 

He is currently partner in the EC project "Simplified and rapid molecular assays for diagnosis of Leishmaniasis and Human African Trypanosomiasis and parasite (sub-)species identification" (TRYLEIDIAG).

 

His expertise covers development and evaluation of parasitological, serological and molecular diagnostics for Kinetoplastida, in particular human and animal African trypanosomiases and leishmaniases.

 

He partcipated in development of the first generation rapid diagnostic tests for gambiense sleeping sickness and for surra.We established and monitor continuously the National Reference Laboratory for Sleeping Sickness in Kinshasa, D.R. Congo.Also has co-ordinated one European Commission project and participated in five others.

 

Current research interests include production and expression of recombinant antigens for serodiagnosis of African trypanosomiaisis in man and animal and for visceral leishmanisis. Syndromic approach to neglected infectious diseases (NID) at primary health care level: an international collaboration on integrated diagnosis-treatment platforms. In vivo tracking of bioluminescent trypanosomes in small rodents, Identification of short diagnostic peptides by Random Phage Display Library screening

Isolation and characterization of drug resistant trypanosomes and development of new generation diagnostics for syphilis

 

The Unit of Parasite Diagnostics is a World Health Organization Collaborating Centre for Research and Training on Human African Trypanosomiasis and is World Animal Health Organization Reference Center for Surra (T. evansi).

 

He is also a steering committee member of the project on African

Trypananosomiasis of GALVmed and regularly acts as expert for the World Health Organization. Awared Brabo Health Development Award 2002, Rotary Club Antwerpen-Schelde, Certification of Appreciation of the International Scientific Committee on Trypanosomiasis Research and Control, 2009 and the Anne Maurer-Cecchini Award, 2014

Unit of Parasite Diagnostics

Department of Biomedical Sciences

Institute of Tropical Medicine

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